Clinical studies of skin rebuilding by hydrolyzed collagen

As we've seen, skin is made of collagen. As we age, collagen production drops off and skin sags because it gets thinner, weaker, drier, and less resilient, or pliable. This deterioration is directly linked to amino acid content. Specific amino acids in skin's structure, like glycine, proline, hydroproline, and alanine - decrease with age and bad diet.

A 2008 study in Tokyo [1] of 33 women ages 40-60 who took hydrolyzed collagen daily for 2 months showed a 91% increase in skin hydration and resilience.

A Dermiscan study in Lyon France in 2008 showed similar findings in an age group of 35-55: an increase in skin smoothness and hydration, using the new Corneometer and Skin Image Analyzer technologies [2,3]. After 12 weeks of hydrolyzed collagen daily, 41% less furrowing, less wrinkles, more resilient, more hydrated. Skin resilience was measured by the C&Z Customer, which is objective and state of the art.

Other scientist have shown exactly how the new collagen is rebuilt, not only in the skin, but in bones and ligaments. Metabolites of hydrolyzed collagen build bone, skin and ligaments by attracting fibroblasts. This is how they trigger synthesis of new collagen [4].

Hydration, or water content of skin tissue, is proven directly related to overall smoothness and decreased furrowing and wrinkling [5].


[1] SOUKEN study Tokyo Japan: two months study hydrolyzed collagen 2008
[2] DERMISCAN study Lyon France Cutaneous properties of hydrolyzed collagen 2008
[3] COURAGE and KHAZAKA study: Moisturizing effect of hydrolyzed collagen measured with Corneometer and Skin Image Analyzer
[4] Posstlethwaite, A - 1978 Chemostatic attraction of juman fibroblasts National Acad. of Sciences vol 75(20) p871
[5] Sumida E The effect of oral ingestion of collagen peptite on skin hydration Journal of Nutritional Food vol 7(3) p45